The ion transporter (IT) superfamily is a
superfamily
SUPERFAMILY is a database and search platform of structural and functional annotation for all proteins and genomes. It classifies amino acid sequences into known structural domains, especially into SCOP superfamilies. Domains are functional, str ...
of secondary carriers that
transport
Transport (in British English), or transportation (in American English), is the intentional movement of humans, animals, and goods from one location to another. Modes of transport include air, land (rail and road), water, cable, pipeline, an ...
charged substrates.
Families
As of early 2016, the currently recognized and functionally defined families that make up the IT superfamily include:
2.A.8-
The Gluconate:H+ Symporter (GntP) Family
2.A.11-
The Citrate-Mg2+:H+ (CitM) Citrate-Ca2+:H+ (CitH) Symporter (CitMHS) Family
2.A.13-
The C4-Dicarboxylate Uptake (Dcu) Family
2.A.14-
The Lactate Permease (LctP) Family
2.A.34-
The NhaB Na+:H+ Antiporter (NhaB) Family
2.A.35-
The NhaC Na+:H+ Antiporter (NhaC) Family
2.A.45-
The Arsenite-Antimonite (ArsB) Efflux Family
2.A.47-
The Divalent Anion:Na+ Symporter (DASS) Family
2.A.61-
The C4-dicarboxylate Uptake C (DcuC) Family
2.A.62-
The NhaD Na+:H+ Antiporter (NhaD) Family
2.A.68-
The p-Aminobenzoyl-glutamate Transporter (AbgT) Family
2.A.94-
The Phosphate Permease (Pho1) Family
2.A.101-
The Malonate Uptake (MatC) Family
2.A.111-
The Na+/H+ Antiporter-E (NhaE) Family
2.A.118-
The Basic Amino Acid Antiporter (ArcD) Family
See also
*
Ion transporter
In biology, a transporter is a transmembrane protein that moves ions (or other small molecules) across a biological membrane to accomplish many different biological functions including, cellular communication, maintaining homeostasis, energy produc ...
s
*
Sodium-Proton antiporter
*
Arsenite-Antimonite efflux
*
Amino acid transporter
An amino acid transporter is a membrane transport protein that transports amino acids. They are mainly of the solute carrier family.
Families
There are several families that function in amino acid transport, some of these include:
TC# 2.A.3- ...
*
Solute carrier family
*
Transporter Classification Database
*
Membrane protein
Membrane proteins are common proteins that are part of, or interact with, biological membranes. Membrane proteins fall into several broad categories depending on their location. Integral membrane proteins are a permanent part of a cell membrane ...
References
Solute carrier family
Protein superfamilies
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